Description

Fasoracetam is a nootropic compound in the racetams group.

• Fasoracetam (N-(5-Oxo-D-prolyl)piperidine) (ref)* and its mechanism of action is not fully understood at this time.

The pre-clinical animal studies, which may not be representative of the effects in humans, indicate that Fasoracetam modulates and activates the metabotropic glutamate receptors (mGluR) (2)*.  Pre-clinical animal studies demonstrate Fasoracetam’s ability to increase acetylcholine release, uptake, and GABAb (3).*

• Since its development in the 1990s in Japan, Fasoracetam studies and human clinical trials have been underway and have demonstrated its safety profile is well tolerated (2)*.
• Assured Purity: Rigorously tested for quality & purity by third-party Certificate of Analysis*

Fasoracetam Chemical Properties

• Molecular formula: C₁₀H₁₆N₂O₂
• Molar mass: 25 g/mol
• CAS number: 110958-19-5 (1)
• Also known as: NS-105 (1)
• Bioavailability in humans*: Peak plasma level in young adults approximately 1.3 hours, and approximately 2.1 hours in elderly (4)
• Bioavailability in the animal model: Peak plasma level within 1 hour (4)(5)
• Systemic bioavailability in the animal model: 90% in dogs, 79% in monkeys, and 97% in rats (5)
• Elimination in the animal model: approximately 90% excreted in urine for rats and monkeys, 60% excreted in dogs (5)
• Half-Life Data in the animal model: 3 hours for monkeys, 2.1 hours for dogs, 0.67 hours for rats (5)